Relationship Between A Premature Rupture Of Membranes And The Increase Of Leucocyte Levels In Pregnant Women During COVID-19 Pandemic

Main Article Content

Rinieta Sausan Margono
Adi Sukrisno
Nunuk Nugrohowati
Winda Lestari

Abstract

Background: Premature Rupture of Membranes (PROM) is a condition in which the membranes rupture before women’s delivery. The incidence of PROM in Indonesia is still quite high, around 4.5%-7.6% from all pregnancies. The incidence rate at DKI Jakarta in 2020 was 4.6% while at Pelni Hospital in the same year was 7.9%. The main cause of this incident was due to the occurrence of infection that spreads into the uterus and amniotic fluid as well as due to the inflammatory process. This causes arachidonic acid metabolism to be active so that the level of leucocytes in the blood being increase. The purpose of this study was to analyze the relationship between the incidence of PROM and leucocyte increasing levels at the Pelni Hospital during the COVID-19 pandemic in 2020.

 Methods: The study had used analytic observational method with cross sectional approach. The number of samples were 97 people, done by simple random sampling technique, using Medical Records of respondents along year of 2020.

 Results: Data showed the aged range of respondents were 20-35 years (79.4%); multigravida (53,6%); PROM (76.3%); respondents with method of delivery which done by cesarean section (71.1%); and respondents with PROM who experienced the increasing of leucocyte levels (80.4%). Results based on Chi-square test showed there was a relationship between PROM and increased leucocyte levels (p=0.036).

 Conclusion: The relationship between PROM and the increasing of leucocyte levels to pregnant women at Pelni Hospital during COVID-19 pandemic in 2020 possibly caused by the presence of infections from ascending microorganisms.

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How to Cite
Relationship Between A Premature Rupture Of Membranes And The Increase Of Leucocyte Levels In Pregnant Women During COVID-19 Pandemic. (2021). Jurnal Kebidanan Dan Kesehatan Tradisional, 127-134. https://doi.org/10.37341/jkkt.v0i0.261
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How to Cite

Relationship Between A Premature Rupture Of Membranes And The Increase Of Leucocyte Levels In Pregnant Women During COVID-19 Pandemic. (2021). Jurnal Kebidanan Dan Kesehatan Tradisional, 127-134. https://doi.org/10.37341/jkkt.v0i0.261

References

Abrar, N. M., Handono, B., dan Triyanti, G. I. (2017). Karakteristik Luaran Kehamilan Dengan Ketuban Pecah Dini Di Rsup Dr. Hasan Sadikin Periode Tahun 2013-2015. Jurnal Sistem Kesehatan, 2(4), 2015–2018. https://doi.org/10.24198/jsk.v2i4.12499

Alfaraj SH, Al-Tawfiq JA, and Memish ZA. (2019). Middle East respiratory syndrome coronavirus (MERS- CoV) infection during pregnancy: report of two cases and review of the literature. J Microbiol Immunol Infect;52:501–3.

Cunningham. (2014). Obstetri Williams. Jakarta : EGC

Darmayani, S., Hasan, F. E., dan A, D. E. (2018). Perbedaan Hasil Pemeriksaan Jumlah Leukosit Antara Metode Manual Improved Neubauer Dengan Metode Automatic Hematology Analyzer. Jurnal Kesehatan Manarang, 2(2), 72. https://doi.org/10.33490/jkm.v2i2.18

Dwi Widyana, E. (2016). Ketuban Pecah Dini (KPD) dan Kadar Leukosit Pada Ibu Bersalin. Jurnal Kesehatan, 4(3).

Emechebe, C.I., Njoku, C.O., Anachuma, K. and Odofa, U. (2015). Determinants and Complications of Pre-Labour Rupture of Membranes (PROM) At the University of Calabar Teaching Hospital (UCTH), Calabar, Nigeria. Scholars Journal of Applied Medical Sciences (SJAMS), 3(5B), 1912–1917.

Fitriyani, Lubis, Y., dan Yuniarti. (2018). Faktor Determinan Pada Ketuban Pecah Dini. Jurnal Media Kesehatan, 11(1), 053–061. https://doi.org/10.33088/jmk.v11i1.357

Hailemariam Segni, T. D. D. and E. A. (2017). Incidence, Maternal and Perinatal Outcome of Premature Rupture of Fetal Membrane Cases in Jimma University Teaching Hospital, South West Ethiopia. EC Gynaecology Research Article, 4(September), 163–172.

Ikrawanty, A., Melisa, F., dan Ana, O. (2019). Faktor-Faktor yang Berhubungan Terhadap Kejadian Ketuban Pecah Dini (KPD) di RSIA Sitti Khadijah I Makassar Tahun 2019. Jurnal Kesehatan Delima Pelamonia, 3(1), 52–61. https://doi.org/10.37337/jkdp.v3i1.110

Ismail, U. (2017). Hubungan paritas, anemia, and usia terhadap kejadian ketuban pecah dini di rsud raden mattaher kota jambi 2017. Scientia Journal, 6(01), 113–119.

Karolina, M. E., Silaban, D. J., Permana, O., dan Suban, B. (2016). Gambaran Hitung Jumlah Dan Jenis Leukosit Serta Pola Makan Pada Komunitas Suku Anak Dalam Di Desa Bukit Suban Dan Sekamis Kabupaten Sarolangun Tahun 2016. Jambi Medical Journal, 5(2), 104–116.

Kementrian Kesehatan RI. (2018). Profil Kesehatan Indonesia 2017. Jakarta: Kemenkes RI. Diakses pada tanggal 31 Januari 2019 dari http://www.depkes.go.id/resources/download/pusdatin/profil-kesehatanindonesia/Profil-Kesehatan-Indonesia-tahun-2017.pdf

Kurniawan, N., Surya, I., Sanjaya, I. N. H., Jaya, M. S., Megadhana, I. W., dan Manuaba, I. F. (2020). Perbedaan kadar c-reactive protein (crp) dan jumlah leukosit serum ibu antara kehamilan aterm normal dengan ketuban pecah dini aterm di RSUP Sanglah Denpasar. Jurnal Medicina, 51(3), 605–610. https://doi.org/10.15562/medicina.v51i3.892

Liu, Y., Chen, H., Tang, K., and Guo, Y. (2020). Clinical manifestations and outcome of SARS-CoV-2 infection during pregnancy. The Journal of Infection. https://doi.org/10.1016/j.jinf.2020.02.028

Manuaba. (2010). Ilmu Kebidanan, Penyakit Kandungan, dan KB. Jakarta: EGC

Merti, D. (2017). Faktor-Faktor Yang Mempengaruhi Ketuban Pecah Dini Di RSU PKU Muhammadiyah Bantul Tahun 2016.

Negara, et. al. (2017). Buku ajar ketuban pecah dini, Jakarta: EGC

Nugroho, Taufan. (2012). Buku Patologi kebidanan, Yogyakarta: Nuha Medika.

Panjaitan, I. M., dan Tarigan, A. M. (2018). Hubungan Karakteristik Ibu Bersalin dengan Ketuban Pecah Dini di Rumah Sakit Martha Friska. Jurnal Bidan Komunitas, 1(2), 67. https://doi.org/10.33085/jbk.v1i2.3938

Poerwoko,F.K., Dewantiningrum, J., Mochtar, A.A., Cahyanti, R.D., Puspasari, D., dan N. A. (2018). Pengaruh Derajat Oligohidramnion terhadap Kejadian Korioamnionitis pada Ketuban Pecah Dini. Medica Hospitalia, 5 (2)(January 2008), 88–91.

Prawiroharjo. (2008). Ilmu kebidanan, Jakarta: Yayasan Bina Pustaka Sarwono Prawiroharjo.

Sherwood, L. (2016). Fisiologi manusia : dari sel ke sistem. Edisi 8. Jakarta: EGC

Shirin, S., and Nahar, S. (2013). Maternal Mortality - A Public Health Problem. Ibrahim Medical College Journal, 6(2), 64–69. https://doi.org/10.3329/imcj.v6i2.14735

Sohail (2012). Etiology of Preterm Premature Ruptur of Membranes. In: Desai S.V., Tank P., editors. Hand Book On Preterm Prelabor Rupture of Membranes in a Low Resource Setting. 1st Ed : New Delhi.Jaypee Brothers Medical Publisher.P 10-21.

Sutjahjo, A. (2016). Dasar-dasar ilmu penyakit dalam, Edisi Pertama, Surabaya: Airlangga University Press (AUP), xvi 160 hlm.

Wang, Y., Wang, H. L., Chen, J., and Sun, J. X. (2016). Clinical and prognostic value of combined measurement of cytokines and vascular cell adhesion molecule-1 in premature rupture of membranes. International Journal of Gynecology and Obstetrics, 132(1), 85–88. https://doi.org/10.1016/j.ijgo.2015.06.059

Wang, H.L., Yang, Z., Shen, Y., and Wang, Q.L. (2018). Clinical outcome of therapeutic cervical cerclage in short cervix syndrome. Jurnal Medicine 25;53(1):43-46. [PubMed: 29374885] 2.